So the "Mars crew" have survived 18 months' isolation without descending into psychosis or even major personality conflicts - unlike some previous experiments which ended up with sexual harassment and violent fist-fights.
One thing they couldn't simulate however is the physiological effect of permanent weightlessness over a sustained period. I believe previous studies have shown this can lead to major loss of bone and muscle tissue. What could be done to counteract these effects in a "live" mission?
